Genomic and Functional Characterization of qnr-Encoding Plasmids from Municipal Wastewater Biosolid Klebsiella pneumoniae Isolates
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چکیده
منابع مشابه
Genomic and Functional Characterization of qnr-Encoding Plasmids from Municipal Wastewater Biosolid Klebsiella pneumoniae Isolates
Municipal wastewater treatment facilities are considered to be "hotspots" for antibiotic resistance, since they conjoin high densities of environmental and fecal bacteria with selective pressure in the form of sub-therapeutic concentrations of antibiotics. Discharged effluents and biosolids from these facilities can disseminate antibiotic resistant genes to terrestrial and aquatic environments,...
متن کاملSequence of Closely Related Plasmids Encoding blaNDM-1 in Two Unrelated Klebsiella pneumoniae Isolates in Singapore
BACKGROUND Spread of the bla(NDM-1) gene that encodes the New Delhi metallo-β-lactamase (NDM-1) in Enterobacteriaceae is a major global health problem. Plasmids carrying bla(NDM-1) from two different multi-drug resistant Klebsiella pneumonia isolates collected in Singapore were completely sequenced and compared to known plasmids carrying bla(NDM-1). METHODOLOGY/PRINCIPAL FINDINGS The two plas...
متن کاملCharacterization co-existence of ESBLs, AmpC and MBLs in Escherichia coli and Klebsiella pneumoniae isolates from Khorramabad Hospitals
Background: Prevalence of co-existence of extended-spectrum β-lactamases (ESBLs), metallo-beta-lactamase (MBLs) and AmpC-β-lactamases producing isolates in these bacteria is a serious problem in treatment of infections. The aim of this study was to characterization co-existence of ESBLs, AmpC and MBLs in Escherichia coli and Klebsiella pneumoniae isolates from Khorramabad hospitals. Materials ...
متن کاملSpread of plasmids containing the bla(VIM-1) and bla(CTX-M) genes and the qnr determinant in Enterobacter cloacae, Klebsiella pneumoniae and Klebsiella oxytoca isolates.
OBJECTIVES We describe 12 VIM-1-producing strains (7 Enterobacter cloacae, 2 Klebsiella pneumoniae and 3 clonal Klebsiella oxytoca strains) detected among clinically relevant Enterobacteriaceae isolates from routine cultures at the Hospital del Mar (Barcelona, Spain) from December 2006 to May 2007. METHODS Susceptibility to carbapenems was evaluated with the MicroScan system. beta-Lactamases ...
متن کاملClosely Related NDM-1-Encoding Plasmids from Escherichia coli and Klebsiella pneumoniae in Taiwan
OBJECTIVE Two plasmids carrying blaNDM-1 isolated from carbapenem-resistant Klebsiella pneumoniae (CR-KP) and carbapenem-resistant Escherichia coli (CR-EC) were sequenced. CR-KP and CR-EC were isolated from two Taiwanese patients without travel histories. METHODS Complete sequencing of the plasmids (pLK75 and pLK78) was conducted using a shotgun approach. Annotation of the contigs was perform...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2015
ISSN: 1664-302X
DOI: 10.3389/fmicb.2015.01354